Protein microarray for characterizing the specificity of the monoclonal immunoglobulins of MGUS or myeloma patients
US9915662B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jul 23, 2013 |
| Grant date | Mar 13, 2018 |
| Priority date | — |
| Expiry date | Feb 17, 2034 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention concerns materials and methods for characterizing monoclonal immunoglobulin specificity of a Monoclonal Gammopathy of Undetermined Significance (MGUS) or Myeloma patients using a protein microarray comprising (a) a substrate, (b) antigens immobilized on the substrate, said antigens being selected from a defined group consisting of infectious agent antigens and/or self-antigens. In particular said protein microarray may be used to improve diagnosis, for the prognosis of myeloma or MGUS, for preventing transformation of MGUS toward myeloma, for adapting treatment of MGUS and myeloma or for monitoring the response to therapy of MGUS and myeloma patients.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.