Methods and means for diagnosing vasculitis

US9915667B2 · kind B2 · utility

Assignee

• MEDIZINISCHE HOCHSCHULE HANNOVER · DE

Inventors

• Torsten Witte · Hannover, DE
• Niklas Thomas Baerlecken · Hannover, DE

Key dates

• Filing date: Jan 27, 2012
• Grant date: Mar 13, 2018
• Expiry date: Jan 27, 2032

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/52
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Provided herein are methods for diagnosing the presence or the risk of development, or for the therapy control of vasculitis, in particular of large vessel vasculitis, like giant-cell arteritis (GCA), polymyalgia rheumatica (PMR), and Takayasu's arteritis, in a subject analyzing for the presence of antibodies against ferritin, in particular heavy chain ferritin or immunoreactive peptides thereof or ferritin analog protein, preferably bacterial ferritin analog protein, or immunoreactive peptides thereof, in a subject. In addition, test kits for use in the diagnosis of the presence or the risk of development, or for the therapy control of vasculitis, in particular of large vessel vasculitis, like GCA, PMR and Takayasu's arteritis, in a subject are also provided.