Substituted oxopyridine derivatives and use thereof as factor XIa/plasma

US9918969B2 · kind B2 · utility

Assignee

• Bayer Pharma Aktiengesellschaft · DE

Inventors

• Susanne Röhrig · Hilden, DE
• Alexander Hillisch · Solingen, DE
• Julia STRAßBURGER · Wuppertal, DE
• Stefan Heitmeier · Wülfrath, DE
• Martina Victoria Schmidt
• Karl-Heinz Schlemmer · Wuppertal, DE
• Anja Buchmüller · Essen, DE
• Christoph Gerdes
• Henrik Teller · Schwaan, DE
• Martina Schäfer · Berlin, DE
• Adrian Tersteegen · Wuppertal, DE

Key dates

• Filing date: Oct 24, 2016
• Grant date: Mar 20, 2018
• Expiry date: Oct 24, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.