Patent · US Active

Process of preparing low ABUK oxymorphone hydrochloride

US9918979B2 · kind B2 · utility

0Cited by

19References

19Claims

0Family size

Assignee

Johnson Matthey Public Limited Company · GB

Inventors

Saroop Singh Matharu · Shirley, US
Brian Heinrich · Fitchburg, US
Aniruddh Singh · Acton, US
Mahmoud Mirmehrabi · Halifax, CA

Key dates

Filing date	Jan 29, 2015
Grant date	Mar 20, 2018
Priority date	—
Expiry date	Jan 29, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D489/08
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

An improved method for the preparation of the low ABUK oxymorphone hydrochloride is provided. The oxymorphone hydrochloride is produced by hydrogenating a starting material comprising oxymorphone base and 14-hydroxymorphinone in a mixture comprising an alcohol, water and an acid, removing some of the water and adding more alcohol to the mixture.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.