Patent · US Active

Nicotinamide mononucleotide derivatives and their uses

US9919003B2 · kind B2 · utility

15Cited by

0References

37Claims

0Family size

Assignee

Metro International Biotech, LLC · US

Inventors

Karl D. Normington · Prides Crossing, US
David A. Sinclair · Feldkirchen-Westerham, DE
David J. Livingston · Barrington, US
James M. McKearin · Litchfield, US
Bruce Szczpankiewicz · Hopkinton, US
Jonathan N. Kremsky · Worcester, US

Key dates

Filing date	Mar 20, 2017
Grant date	Mar 20, 2018
Priority date	—
Expiry date	Mar 20, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07H19/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to compositions of nicotinamide mononucleotide derivatives and their methods of use. The invention also relates to methods of preparing nicotinamide mononucleotide derivatives. The invention relates to pharmaceutical compositions and nutritional supplements containing a nicotinamide mononucleotide derivative. The invention relates to methods of using nicotinamide mononucleotide derivatives that promote the increase of intracellular levels of nicotinamide adenine dinucleotide (NAD+) in cells and tissues for treating diseases and improving cell and tissue survival.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.