Sugar-linker-drug conjugates
US9919055B2 · kind B2 · utility
2Cited by
2References
17Claims
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Assignee
Inventors
Key dates
| Filing date | Mar 14, 2014 |
| Grant date | Mar 20, 2018 |
| Priority date | — |
| Expiry date | Mar 15, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure relates to sugar-linker-drug conjugates, of the formula [A-B-]n-L-D, wherein A is a saccharide; B is a spacer, n is an integer selected from 1 to 3; L is a linker group and D is a drug having a chemically reactive functional group selected from the group consisting of a primary or secondary amine, hydroxyl, sulfhydryl, carboxyl, aldehyde and ketone. Pharmaceutical compositions comprising the conjugates and methods of using them are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.