Iontophoresis drug delivery system and method for denervation of the renal sympathetic nerve and iontophoretic drug delivery
US9919144B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | May 6, 2015 |
| Grant date | Mar 20, 2018 |
| Priority date | — |
| Expiry date | Jun 20, 2035 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2025/1086
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
An iontophoresis drug delivery system and method for denervation of the renal sympathetic nerve and iontophoresis drug delivery. The system includes an iontophoresis catheter fitted with a drug coated balloon. The iontophoresis catheter includes a balloon near its distal tip or end that contacts the vessel wall circumferentially when inflated. One or more electrodes are associated with a surface of the balloon, and may be disposed on an outer surface of the balloon. The electrodes are operably coupled to an energy source configured to produce a bipolar or monopolar electric field between two balloon electrodes and/or between one balloon electrode and another electrode placed in contact with a part of the patient's body. During use, the disclosed drug-delivery catheter produces an electric potential gradient within adjacent tissue, that, in turn, facilitates iontophoresis delivery of a drug. The disclosed catheter can also include a store of one or more drugs to be delivered to the targeted tissue.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.