Patent · US Active

Process for the preparation of 4-amino 1-((1S,4R,5S)-2-fluoro-4,5-dihydroxy-3-hydroxymethyl-cyclopent-2-enyl)-1H-pyrimidin-2-one

US9920016B2 · kind B2 · utility

0Cited by

5References

16Claims

0Family size

Assignee

REXAHN PHARMACEUTICALS, INC. · US

Inventors

Deog Joong Kim · Rockville, US
Haifeng Yin · Shanghai, CN
Eliezer Falb · Givatayim, IL
Leigh Andre Pearcey · Biggenden, AU
Jonathan Cummins · Biggenden, AU
Petra Dieterich · Abingdon, GB
Jean-Francois Carniaux · Abington, GB
Yi Wang · Chester Springs, US
Vikram Purohit · Downingtown, US

Key dates

Filing date	Dec 15, 2016
Grant date	Mar 20, 2018
Priority date	—
Expiry date	Dec 15, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07F7/1892
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Processes for the preparation of 4-amino-1-((1S,4R,5S)-2-fluoro-4,5-dihydroxy-3 -hydroxymethyl-cyclopent-2-enyl)-1H-pyrimidin-2-one(13, RX-3117) and its intermediates are described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.