Patent · US Active

Crystalline form of a substituted quinoline compound and pharmaceutical compositions thereof

US9920033B2 · kind B2 · utility

2Cited by
1References
10Claims
0Family size

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Key dates

Filing dateNov 12, 2016
Grant dateMar 20, 2018
Priority date
Expiry dateNov 12, 2036

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07B2200/13
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to a crystalline form of N-(3-fluoro-4-((7-(2-hydroxy-2-methylpropoxy)quinolin-4-yl)oxy)phenyl)-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide p-toluenesulfonate, the process for preparing the crystalline form thereof, and the pharmaceutical compositions comprising the crystalline form thereof. This invention also relates to a method of using such a crystalline form and pharmaceutical compositions comprising the crystalline form thereof in the treatment of hyperproliferative diseases in mammals, especially in humans.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.