Methods of producing immunoconjugates
US9920124B2 · kind B2 · utility
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19Claims
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Key dates
| Filing date | Dec 19, 2013 |
| Grant date | Mar 20, 2018 |
| Priority date | — |
| Expiry date | Dec 19, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides methods of preparing active immunoconjugates, including anti-CD22 immunoconjugates. Suitably, the methods include a fed-batch refolding process and/or column stripping process that result in an increase in yield of the immunoconjugate over other processes that do not utilize the methods.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.