Methods for producing virus particles with simplified glycosylation of surface proteins
US9920347B2 · kind B2 · utility
2Cited by
8References
10Claims
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Key dates
| Filing date | May 26, 2016 |
| Grant date | Mar 20, 2018 |
| Priority date | — |
| Expiry date | May 26, 2036 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/52
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods for producing virus particles and viral antigens with simplified glycosylation profiles, such as mono-glycosylated forms of HIV, HCV, Dengue virus, West Nile virus and influenza virus. When used as targets for vaccine production, the conserved nature of such sites generate vaccines that are less sensitive to viral mutations. Such methods may include the use of glycosylation inhibitors for production of viruses or viral antigens with simplified glycosylation profiles.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.