Nanoelectronic-enzyme linked immunosorbent assay system and method
US9921216B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 30, 2015 |
| Grant date | Mar 20, 2018 |
| Priority date | — |
| Expiry date | Mar 23, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/98
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to a device and method for determining the presence of a specific compound in solution. The device includes a nanosensor having an electrically conducting pathway between at least a first and second contact. The device also includes a first receptor, suitable for binding a specific compound in the solution, attached to the nanosensor, and a second receptor also suitable for binding the specific compound while the specific compound is bound to the first receptor. The second receptor is attached to an enzyme added to the solution. When the solution having the second receptor is added to the device, and a second compound that is a substrate for the enzyme is subsequently added to the solution, a measured difference in an electrical property in the device before and after the application of the second compound is indicative of the presence of the specific compound in the solution.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.