Methods of using compositions comprising variants and fusions of FGF19 polypeptides for treatment of nonalcoholic steatohepatitis
US9925242B2 · kind B2 · utility
25Cited by
58References
52Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 26, 2013 |
| Grant date | Mar 27, 2018 |
| Priority date | — |
| Expiry date | Dec 26, 2033 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to variants and fusions of fibroblast growth factor 19 (FGF19), variants and fusions of fibroblast growth factor 21 (FGF21), fusions of FGF19 and/or FGF21, and variants or fusions of FGF19 and/or FG-F21 proteins and peptide sequences (and peptidomimetics), having one or more activities, such as bile acid homeostasis modulating activity, and methods for and uses in treatment of bile acid and other disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.