Liquid pharmaceutical formulations for injection comprising procaine and uses thereof
US9925263B2 · kind B2 · utility
2Cited by
67References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 11, 2014 |
| Grant date | Mar 27, 2018 |
| Priority date | — |
| Expiry date | Mar 20, 2036 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/54
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Concentrated, low-viscosity, low-volume liquid pharmaceutical formulations of proteins have been developed. Such formulations can be rapidly and conveniently administered by subcutaneous or intramuscular injection, rather than by lengthy intravenous infusion. These formulations include low-molecular-weight and/or high-molecular-weight proteins, such as mAbs, and viscosity-lowering agents that are typically bulky polar organic compounds, such as many of the GRAS (US Food and Drug Administration List of compounds generally regarded as safe) and inactive injectable ingredients and FDA approved therapeutics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.