Method for combinatorial particle manipulation for producing high-density molecule arrays, in particular peptide arrays, and molecule arrays that can be obtained by means thereof

US9925509B2 · kind B2 · utility

Assignee

• PEPperPRINTGmbH (DE/DE) · DE

Inventors

• Frieder Märkle · Karlsruhe, DE
• Alexander Nesterov-Müller · Philippsburg, DE
• Frank Breitling · Heidelberg, DE
• Felix Löffler · Heidelberg, DE
• Sebastian Mathias SCHILLO · Karlsruhe, DE
• Valentina Bykovskaya · Karlsruhe, DE
• Clemens Matthias von Bojnicic-Kninski · Karlsruhe, DE
• Klaus Leibe · Leimen, DE

Key dates

• Filing date: Apr 17, 2014
• Grant date: Mar 27, 2018
• Expiry date: Jul 27, 2034

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01J2219/00725
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to a method for combinatorial particle manipulation for producing high-density molecule arrays, and to the high-density molecule arrays obtained therefrom. In particular, the present invention relates to a method for producing high-density molecule arrays, in particular peptide or oligonucleotide arrays, by combinatorial patterning of particles, wherein the patterning is achieved by the selective and direct action of electromagnetic radiation.