N-cyclopropyl-N-piperidinyl-amides, pharmaceutical compositions containing them and uses thereof

US9926308B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Bernd Nosse · Biberach an der Riß, DE
• Matthias Eckhardt · Hannover, DE
• Frank Himmelsbach · Mittelbiberach, DE
• Elke Langkopf · Biberach an der Riß, DE
• Neil Ashweek · San Diego, US
• Nicole Harriott · San Diego, US

Key dates

• Filing date: Feb 16, 2016
• Grant date: Mar 27, 2018
• Expiry date: Feb 16, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of formula Iwherein R1, LP, n, HetAr1, and HetAr2 are as defined herein, and salts thereof, pharmaceutical compositions containing these compounds, and methods for treating diseases or conditions which are mediated by activating the G-protein-coupled receptor GPR119, such as diabetes, dislipidemia, or obesity, by administering to a patient in need thereof these compounds or a pharmaceutically acceptable salt thereof.