Patent · US Active

Compositions and methods for modulation of SMN2 splicing in a subject

US9926559B2 · kind B2 · utility

10Cited by

21References

10Claims

0Family size

Assignee

Biogen MA Inc. · US

Inventors

C. Frank Bennett · Carlsbad, US
Gene Hung · San Francisco, US
Frank Rigo · Carlsbad, US

Key dates

Filing date	Jan 9, 2014
Grant date	Mar 27, 2018
Priority date	—
Expiry date	Jan 9, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/156
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed herein are compounds, compositions and methods for modulating splicing of SMN2 mRNA in a subject. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders, including spinal muscular atrophy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.