Patent · US Active

Multiplex microarray of serially deposited biomolecules on a microarray

US9927434B2 · kind B2 · utility

2Cited by
32References
20Claims
0Family size

Assignee

Inventor

Key dates

Filing dateJan 20, 2011
Grant dateMar 27, 2018
Priority date—
Expiry dateSep 21, 2032

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N33/5438
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Disclosed herein is a multiplex microarray having serially attached non-functionalized biomolecules attached to a polymer coating covering each electrode of an array of electrodes for assays and a method of making the multiplex microarray. The method comprises serially blocking the electrodes of the microarray with a blocking protein, electropolymerizing pyrrole or a functionalized pyrrole on the electrodes where the biomolecule is not present during polymerization, exposing the microarray to a biomolecular solution containing a non-functionalized biomolecule for attachment to the polymer coating, and then repeating the steps to form the multiplex microarray.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.