Methods of reducing clinical symptoms of viral infection by administering a toll-like receptor 3 antagonist

US9932404B2 · kind B2 · utility

Assignee

• JANSSEN BIOTECH, INC. · US

Inventors

• Mark Cunningham · Kennett Square, US
• Yiqing Feng · Chesterfield, US
• Katharine Heeringa · Spring House, US
• Jinquan Luo · Malvern, US
• Robert Rauchenberger · Martinsried, DE
• Mark Rutz · Martinsried, DE
• Lani San Mateo · Radnor, US
• Robert Sarisky · Lansdale, US
• Raymond Sweet · Via Enrico Fermi, US
• Fang Teng · Radnor, US
• Alexey Teplyakov · Spring House, US
• Sheng-Jiun Wu · Broomall, US

Key dates

• Filing date: Nov 8, 2016
• Grant date: Apr 3, 2018
• Expiry date: Nov 8, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2310/17
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.