Dyes and compositions, and processes for using same in analysis of protein aggregation and other applications
US9932479B2 · kind B2 · utility
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7Claims
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Key dates
| Filing date | Jul 29, 2015 |
| Grant date | Apr 3, 2018 |
| Priority date | — |
| Expiry date | Jun 18, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/2835
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Provided are dyes and compositions which are useful in a number of applications, such as the detection and monitoring protein aggregation, kinetic studies of protein aggregation, neurofibrillary plaques analysis, evaluation of protein formulation stability, protein thermal stability shift assay and analysis of molecular chaperone activity. These dyes and compositions are also useful as probes in nucleic acid and protein detection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.