Engineered imine reductases and methods for the reductive amination of ketone and amine compounds
US9932613B2 · kind B2 · utility
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7Claims
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Key dates
| Filing date | Oct 24, 2017 |
| Grant date | Apr 3, 2018 |
| Priority date | — |
| Expiry date | Oct 24, 2037 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/52
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present disclosure provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered imine reductases, host cells capable of expressing the engineered imine reductases, and methods of using these engineered polypeptides with a range of ketone and amine substrate compounds to prepare secondary and tertiary amine product compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.