Patent · US Active

Therapeutic antibodies against ROR-1 protein and methods for use of same

US9933434B2 · kind B2 · utility

11Cited by

192References

11Claims

0Family size

Assignee

The Regents of the University of California · US

Inventors

Thomas J. Kipps · San Diego, US
George F. Widhopf, II · San Diego, US
Bing Cui · San Diego, US

Key dates

Filing date	Nov 9, 2016
Grant date	Apr 3, 2018
Priority date	—
Expiry date	Nov 9, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Therapeutic antibodies having binding specificity for ROR-1 expressed on cancer cells (particularly leukemic and lymphomic cells) and pharmaceutical compositions containing one or more such antibodies for use in treating cancer. Methods for diagnosing such cancers through in vitro detection of binding to ROR-1 protein expressed on putative cancer cells are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.