Patent · US Active

Trilayer coated pharmaceutical packaging with low oxygen transmission rate

US9937099B2 · kind B2 · utility

18Cited by
637References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 26, 2015
Grant dateApr 10, 2018
Priority date
Expiry dateJun 26, 2035

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T428/1383
  • WIPO fieldMedical technology
  • WIPO sectorInstruments

Abstract

An article is described including an article surface and a coating set comprising an optional tie coating or layer, a barrier coating or layer, and a pH protective layer. The respective coatings or layers can be applied by chemical vapor deposition of a polysiloxane or polysilazane precursor in the presence of oxygen. Examples of such an article are a prefilled thermoplastic syringe or thermoplastic pharmaceutical vial with a coated interior portion containing a pharmaceutical preparation or other fluid with a pH of 4 to 8, alternatively 5 to 9. The barrier coating or layer prevents oxygen from penetrating into the thermoplastic syringe or vial. The tie coating or layer, if present, and the pH protective coating or layer protect the barrier layer from the contents of the syringe or vial.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.