Palonosetron oral transmucosal film or patch
US9937122B2 · kind B2 · utility
17Cited by
2References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 12, 2016 |
| Grant date | Apr 10, 2018 |
| Priority date | — |
| Expiry date | Jul 12, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P1/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a pharmaceutical composition for delivering palonosetron through the buccal mucosa or sublingual mucosa. The pharmaceutical composition comprises 0.05-35% (w/w) of palonosetron, 40-90% of a film forming agent, 1-10% (w/w) of a plasticizer, 5-25% (w/v) of an adhesive agent, and 0.1-5% of a penetration enhancing agent. A preferred plasticizer is a polysorbate. A preferred adhesive agent is polyvinylpyrrolidone or carboxymethylcellulose. A preferred penetration enhancing agent is peppermint oil or menthol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.