Patent · US Active

Constrained tricyclic sulfonamides

US9937180B2 · kind B2 · utility

0Cited by

5References

18Claims

0Family size

Assignee

ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · US

Inventors

Michael Ohlmeyer · Plainsboro, US
David Kastrinsky · Fair Lawn, US

Key dates

Filing date	Mar 10, 2015
Grant date	Apr 10, 2018
Priority date	—
Expiry date	Mar 10, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C2603/32
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Tricyclic chemical modulators of protein phosphatase 2A are disclosed. The compounds are useful to treat cancer, age-onset proteotoxicity, stress-induced depression, inflammation, and acne. The compounds are of the following phenothiazine and dibenzoazepine compounds and similar genera:

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.