Combination therapy comprising a liposomal prodrug of mitomycin C and radiotherapy
US9937261B2 · kind B2 · utility
1Cited by
4References
20Claims
0Family size
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Key dates
| Filing date | Jun 9, 2015 |
| Grant date | Apr 10, 2018 |
| Priority date | — |
| Expiry date | Jun 9, 2035 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of treating neoplasia in a subject in need of treatment is provided by administering to the subject an amount of a prodrug of mitomycin C that yields a therapeutically effective amount of mitomycin C, in combination with radiation therapy. In one embodiment, the prodrug of mitomycin C is a liposomal-prodrug of mitomycin C. Together, the prodrug of mitomycin C and radiation therapy provide a synergistic antineoplastic effect.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.