Biocompatible and biodegradable gradient layer system for regenerative medicine and for tissue support

US9937278B2 · kind B2 · utility

Assignee

• AMOR (SUZHOU) MEDICAL SCI-TECH CO., LTD. · CN

Inventors

• Thorsten Steinberg · Mannheim, DE
• Pascal Tomakidi · Teningen, DE
• Simon Schulz · Bad Mergentheim, DE
• Marco Angarano · Ettlingen, DE
• Rolf Muelhaupt · Glückstadt, DE
• Martin Fabritius · Glückstadt, DE

Key dates

• Filing date: Apr 4, 2012
• Grant date: Apr 10, 2018
• Expiry date: Apr 4, 2032

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61L2420/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention is directed to a biocompatible and preferably biodegradable gradient layer system comprising at least one set of layers comprising a biocompatible and preferably biodegradable cross-linked polymer and at least one biocompatible and preferably biodegradable support layer, wherein a gradient is preferably formed with respect to the mechanical and/or physical properties of one or more layers of the at least one set of layers comprising a biocompatible and biodegradable cross-linked polymer and/or the at least one biocompatible and preferably biodegradable support layer. The at least one support layer preferably comprises a biocompatible and preferably biodegradable meltable polymer and/or a biocompatible and incorporable material. This biocompatible and preferably biodegradable gradient layer system may be used as a biomaterial for regenerative medicine, particularly as a wound dressing or for tissue support. The present invention also provides means utilizing said inventive gradient layer system and methods for producing same.