Compounds with neural protective effect, and preparation and use thereof
US9938235B2 · kind B2 · utility
Inventors
Key dates
| Filing date | Mar 2, 2015 |
| Grant date | Apr 10, 2018 |
| Priority date | — |
| Expiry date | Mar 2, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2602/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention generally relates to compounds of formula (I) with neural protective effect, and preparation and uses thereof.The compounds have multiple mechanisms or functions, for example, inhibition of monoamine oxidase and cholinesterase, scavenging of free radicals, and protection of cells such as nerve cells. The compounds can be used for manufacture of medicaments of cell protection, for prevention and/or treatment of monoamine oxidase, cholinesterase and free radicals related diseases, for example, neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and stroke, and free-radical related diseases such as heart disease, myocardial ischemia, diabetes and other cardiovascular and cerebrovascular diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.