Patent · US Active

C-ring modified tricyclic benzonaphthiridinone protein kinase inhibitors and use thereof

US9938268B2 · kind B2 · utility

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0References

2Claims

0Family size

Assignee

Merck Patent GmbH · DE

Inventors

Yufang Xiao · Lexington, US
Bayard R. Huck · Sudbury, US
Amanda E. Sutton · Hingham, US
Thomas E. Richardson · Durham, US
Srinivasa Karra · Pembroke, US

Key dates

Filing date	Dec 2, 2009
Grant date	Apr 10, 2018
Priority date	—
Expiry date	Dec 14, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D495/14
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed are C-ring modified tricyclic benzonaphthiridinone compounds and analogs thereof, pharmaceutical compositions comprising such compounds and processes for preparing the same. The compounds are useful in the treatment of diseases amenable to protein kinase signal transduction inhibition, regulation and/or modulation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.