Quinoline derivatives as SMO inhibitors

US9938292B2 · kind B2 · utility

Assignee

• GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD · CN

Inventors

• Hao Wu · Shanghai, CN
• Chaofeng Long · Tangxia, CN
• Jun Lin · Taoyuan, TW
• Xiaoxin Chen · Cupertino, US
• Yunhui Li · Shanghai, CN
• Zhuowei Liu · 流花街道, CN
• Changqing Wei · Shanghai, CN
• Lijuan Chen · Dongguan, CN
• Shuhui CHEN · Shanghai, CN

Key dates

• Filing date: Mar 16, 2015
• Grant date: Apr 10, 2018
• Expiry date: Mar 16, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D498/08
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Disclosed are quinoline derivatives as hedgehog pathway inhibitors, especially as SMO inhibitors. Compounds of the present invention can be used in treating diseases relating to hedgehog pathway including cancer.