Methods for identifying modulators of Ras using nonlinear techniques
US9938560B2 · kind B2 · utility
2Cited by
32References
11Claims
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Key dates
| Filing date | Nov 2, 2012 |
| Grant date | Apr 10, 2018 |
| Priority date | — |
| Expiry date | Dec 7, 2034 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2458/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided herein are compositions and methods for identifying and detecting modulators of Ras protein conformational states through the use of second harmonic generation (SHG) technology. Also provided herein are methods for detecting a conformational changes in the three dimensional structure of a protein bound to a supported lipid bilayer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.