Automated control of micromanipulator arm for histotripsy prostate therapy while imaging via ultrasound transducers in real time

US9943708B2 · kind B2 · utility

Assignees

• HistoSonics, Inc. · US
• THE REGENTS OF THE UNIVERSITY OF MICHIGAN · US

Inventors

• William W. Roberts · Tallahassee, US
• Timothy L. Hall · Ann Arbor, US
• Charles A. Cain · Ann Arbor, US
• J. Brian Fowlkes · Ann Arbor, US
• Zhen Xu · Ann Arbor, US
• Michael T. Kusner · Ann Arbor, US
• Dejan Teofilovic · Ann Arbor, US

Key dates

• Filing date: Aug 26, 2010
• Grant date: Apr 17, 2018
• Expiry date: Jan 31, 2032

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61B2090/378
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A medical imaging and therapy device is provided that may include any of a number of features. One feature of the device is that it can image a target tissue volume and apply ultrasound energy to the target tissue volume. In some embodiments, the medical imaging and therapy device is configured controllably apply ultrasound energy into the prostate by maintaining a cavitational bubble cloud generated by an ultrasound therapy system within an image of the prostate generated by an imaging system. The medical imaging and therapy device can be used in therapeutic applications such as Histotripsy, Lithotripsy, and HIFU, for example. Methods associated with use of the medical imaging and therapy device are also covered.