Patent · US Active

Inhibitors of cellular necrosis and related methods

US9944628B2 · kind B2 · utility

1Cited by

46References

12Claims

0Family size

Assignees

President and Fellows of Harvard College · US
SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES · CN

Inventors

Junying Yuan · Newton, US
Yijun Zhou · Lund, SE
Shan Qian · Shanghai, CN
Dawei Ma · Shanghai, CN

Key dates

Filing date	Dec 11, 2015
Grant date	Apr 17, 2018
Priority date	—
Expiry date	Dec 11, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D233/78
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

A compound having the following structure (I):or a pharmaceutically acceptable salt, prodrug, stereoisomer or tautomer thereof, is provided. Related compounds, methods for preparation of the same and uses of the compounds for treatment of various indications, including treatment of necrotic cell diseases and/or inflammation, are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.