Fumarate-CO-releasing molecule hybrids, their use in the treatment of inflammatory or cardiovascular diseases and their process of preparation
US9944669B2 · kind B2 · utility
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Key dates
| Filing date | Mar 20, 2015 |
| Grant date | Apr 17, 2018 |
| Priority date | — |
| Expiry date | Mar 20, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F15/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to hybrid fumarate-CO-releasing molecules capable of increasing heme oxygenase-1 (HO-1) activity and HO-1 protein expression and simultaneously releasing CO, their synthesis and their use in therapeutic applications, in particular their use in the treatment of inflammatory or cardiovascular diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.