Patent · US Active

Recombinant Escherichia coli for producing D-lactate and use thereof

US9944957B2 · kind B2 · utility

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12Claims

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Assignee

TIANJIN INSTITUTE OF INDUSTRIAL BIOTECHNOLOGY, CHINESE ACADEMY OF SCIENCES · CN

Inventors

Yanhe Ma · Tianjin, CN
Xueli Zhang · Tianjin, CN
Hongtao Xu · Tianjin, CN
Xinna Zhu · Tianjin, CN
Pingping LIU · Shanghai, CN
Jinlei TANG · Tianjin, CN

Key dates

Filing date	Jul 9, 2014
Grant date	Apr 17, 2018
Priority date	—
Expiry date	Jan 5, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y101/01028
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Provided is recombinant Escherichia coli comprising a mutated ldhA gene. Disclosed are use of the recombinant Escherichia coli in the preparation of D-lactate, and method of preparing D-lactate by employing the recombinant Escherichia coli. In the method of preparing D-lactate, fermentation can be conducted at a high temperature (42-50° C.), and aqueous ammonia or sodium hydroxide can be used as a neutralizer during the fermentation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.