Coiled coil helix cristae morphology 1 (CHCM1) tumor marker and cancer therapeutic target
US9945863B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 16, 2013 |
| Grant date | Apr 17, 2018 |
| Priority date | — |
| Expiry date | Jan 14, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/57484
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods for diagnosing and treating a cancer or a tumor in a patient are provided. The methods can comprise the steps of obtaining a biological sample from the patient and analyzing the sample for the presence or absence of Coiled Coil Helix Cristae Morphology 1 protein (CHCM1). A patient is diagnosed with cancer or a tumor provided that CHCM1 is overexpressed. The diagnosed patient is treated by administering a cancer or tumor treatment. The methods can also comprise the steps of obtaining a sample of cancer or tumor cells from the patient, determining a level of CHCM1 expression in the sample of cancer or tumor cells, and administering to the patient a compound for reducing the expression of CHCM1 or for blocking or inhibiting function of CHCM1.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.