Composition comprising active ingredient, oil and ionic liquid

US9949475B2 · kind B2 · utility

Inventors

• Vandana Kurkal-Siebert · Heidelberg, DE
• Ann-Kathrin Marguerre · Mannheim, DE
• Daher Michael Badine · Mannheim, DE
• Ulrike Troppmann · Schifferstadt, DE
• Ansgar Schäfer · Karlsruhe, DE
• Sebastian Koltzenburg · Schifferstadt, DE
• Karolin Geyer · Mannheim, DE
• Murat Cetinkaya · Heidelberg, DE
• Eduard Schreiner · Bochum, DE
• Nikolaus Nestle · Heidelberg, DE
• Andreas Hopf · Neustadt, DE
• Ingolf Hennig · Neulußheim, DE
• Karsten Seidel · Mannheim, DE
• Jurgen Mertes · Gau-Algesheim, DE

Key dates

• Filing date: Aug 14, 2012
• Grant date: Apr 24, 2018
• Expiry date: Aug 23, 2032

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2800/591
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to a liquid composition comprising A) an organic active ingredient which is sparingly water-soluble and sparingly oil-soluble, in dissolved form, B) an oil which is soluble in water at 20° C. to at most 20 g/l, and C) an ionic liquid comprising a cation and an anion as described below. Also provided is a process for the preparation of the liquid composition, where the active ingredient, the oil and the ionic liquid are brought into contact; and also the use of the ionic liquid for increasing the solubility of the active ingredient in an oil.