Bis-polymer lipid-peptide conjugates and nanoparticles thereof
US9949927B2 · kind B2 · utility
3Cited by
2References
34Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 18, 2014 |
| Grant date | Apr 24, 2018 |
| Priority date | — |
| Expiry date | Sep 18, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/42
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides bis-polymer lipid-peptide conjugates containing a hydrophobic block and headgroup containing a helical peptide and two polymer blocks. The conjugates can self-assemble to form helix bundle subunits, which in turn assemble to provide micellar nanocarriers for drug cargos and other agents. Particles containing the conjugates and methods for forming the particles are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.