Patent · US Active

Methods of treating aquaporin-mediated conditions

US9949991B2 · kind B2 · utility

10Cited by
16References
17Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 6, 2014
Grant dateApr 24, 2018
Priority date
Expiry dateNov 6, 2034

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07F9/09
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to the use of selective aquaporin inhibitors, e.g., of aquaporin-4 or aquaporin-2, e.g., certain phenylbenzamide compounds, for the prophylaxis, treatment and control of aquaporin-mediated conditions, e.g., glioblastoma and ovarian hyperstimulation syndrome. The invention provides, inter alia, methods of treating or controlling a disease condition mediated by an aquaporin, e.g., diseases or conditions of water imbalance and other diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.