Methods for preventing or treating disorders by increasing bioavailability of iron and related pharmaceutical formulation

US9950034B2 · kind B2 · utility

Assignee

• Pieris Pharmaceuticals GmbH · DE

Inventors

• Andreas Hohlbaum · Paunzhausen, DE
• Hendrik Gille · Berlin, DE
• Stefan Trentmann · Freising, DE
• Laurent Audoly · Mahwah, US
• Andrea Allersdorfer · Wolnzach, DE

Key dates

• Filing date: Feb 16, 2017
• Grant date: Apr 24, 2018
• Expiry date: Feb 16, 2037

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/347
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present disclosure relates to methods of treating, ameliorating or preventing a disorder comprising administering a therapeutically effective amount of a composition to a subject in need thereof, which composition contains a lipocalin mutein or a fragment or a variant thereof capable of increasing the bioavailability of iron in the subject.