Vaccines based on hepatitis B core antigens
US9950050B2 · kind B2 · utility
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2References
28Claims
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Assignee
Inventors
Key dates
| Filing date | Feb 18, 2015 |
| Grant date | Apr 24, 2018 |
| Priority date | — |
| Expiry date | Feb 18, 2035 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides a protein comprising hepatitis B core antigen (HBcAg) with a sugar attached to an e1 loop. The protein may comprise a first and a second copy of HBcAg in tandem, wherein one or both copies of HBcAg has a sugar attached to the e1 loop. The first copy may have a sugar attached to the e1 loop and the second copy may comprise a peptide epitope in the e1 loop. The protein may be used to induce an immune response against the sugar and hence act as a vaccine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.