Particles comprising a shell with RNA

US9950065B2 · kind B2 · utility

Assignees

• BIONTECH RNA PHARMACEUTICALS GMBH · DE
• TRON—Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg-Universität Mainz · DE

Inventors

• Ugur Sahin · Mainz, DE
• Heinrich Haas · Mainz, DE
• Sebastian Kreiter · Mainz, DE
• Yves Hüsemann · Wiesbaden, DE
• Mustafa Diken · Mainz, DE
• Kerstin Reuter · Darmstadt, DE
• Hossam Hefresha · Wiesbaden, DE

Key dates

• Filing date: Sep 26, 2013
• Grant date: Apr 24, 2018
• Expiry date: Sep 26, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2810/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to RNA decorated particles such as RNA decorated lipid particles, preferably to RNA decorated liposomes. Further, the present invention relates to a pharmaceutical composition comprising RNA decorated particles such as RNA decorated lipid particles, preferably RNA decorated liposomes. Said pharmaceutical composition is useful for inducing an immune response. It is also useful in a prophylactic and/or therapeutic treatment of a disease involving an antigen. Furthermore, the present invention relates to a method for producing the RNA decorated particles such as RNA decorated lipid particles, preferably RNA decorated liposomes.