Peptide sequence design and use thereof for peptide-mediated siRNA delivery
US9950073B2 · kind B2 · utility
1Cited by
2References
18Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Jan 17, 2017 |
| Grant date | Apr 24, 2018 |
| Priority date | — |
| Expiry date | Jan 17, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/51
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Peptides that have been found to facilitate the delivery of siRNA molecules into cells and to function in siRNA mediated silencing of cellular targets are disclosed. Complexes that include one of the peptides and a cargo molecule are disclosed, wherein the peptide and the cargo molecule are coupled non-covalently. Also disclosed are methods of producing and using the peptides/complexes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.