2-acylaminothiazole derivative or salt thereof
US9951060B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 5, 2015 |
| Grant date | Apr 24, 2018 |
| Priority date | — |
| Expiry date | Jun 5, 2035 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/497
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
[Problem]To provide a compound which is useful as an active ingredient for a pharmaceutical composition for preventing or treating urine storage dysfunction, voiding dysfunction, lower urinary tract dysfunction, and the like.[Means for Solution]The present inventors have found that a thiazole derivative substituted with pyrazinylcarbonylamino at the 2-position is an excellent muscarinic M3 receptor-positive allosteric modulator and is expected as an agent for preventing or treating bladder/urinary tract diseases associated with bladder contractions via a muscarinic M3 receptor, thereby completing the present invention. 2-Acylaminothiazole derivative or a salt thereof of the present invention is expected as an agent for preventing or treating bladder/urinary tract diseases associated with bladder contractions via a muscarinic M3 receptor, for example voiding dysfunction such as underactive bladder.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.