Antibody-drug conjugates, their preparation and their therapeutic use
US9951141B2 · kind B2 · utility
9Cited by
4References
54Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 1, 2015 |
| Grant date | Apr 24, 2018 |
| Priority date | — |
| Expiry date | Jun 1, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure relates to conjugates comprising biologically active molecules linked to a multimeric antigen-binding compound or a multimeric immunoglobulin via a linker. The disclosure further provides reagents and methods of manufacturing the conjugates and the linkers. The disclosure also provides compositions comprising the conjugates, methods of modifying abnormal cell growth and methods of treatment using the conjugates or the compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.