Amphiphilic blockcopolymers comprising reduction sensitive biodegradable polyesteramides
US9951183B2 · kind B2 · utility
1Cited by
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20Claims
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Assignee
Inventors
Key dates
| Filing date | Aug 10, 2015 |
| Grant date | Apr 24, 2018 |
| Priority date | — |
| Expiry date | Aug 10, 2035 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/34
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to amphiphilic block copolymers comprising reduction sensitive biodegradable polyesteramides. The present invention also relates to micelles comprising the amphiphilic block copolymers. The invention also relates to drug delivery systems comprising the micelles. The amphiphilic block copolymers comprise hydrophilic and hydrophobic blocks whereby the hydrophobic blocks comprise a biodegradable polyesteramide based on alpha-amino acids, diols, aliphatic dicarboxylic acids and optionally diamines whereby at least one of the dicarboxylic acids, diols or diamines comprises disulphide linkages.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.