Monoazo dyes with cyclic amine as fluorescence quenchers
US9951227B2 · kind B2 · utility
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Key dates
| Filing date | Sep 7, 2017 |
| Grant date | Apr 24, 2018 |
| Priority date | — |
| Expiry date | Sep 7, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2565/101
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present disclosure provides reactive quencher dyes that can be used in the detection and/or quantification of desirable target molecules, such as proteins, nucleic acids and various cellular organelles. These dyes are essentially non-fluorescent but are efficient quenchers of various fluorescent dyes. Also, provided are methods of using the dyes, bio-probes incorporating dyes and methods of using the bio-probes. The quencher dyes described herein are modified to provide beneficial properties.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.