Process for particle processing of active pharmaceutical ingredients
US9956144B2 · kind B2 · utility
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4References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 21, 2011 |
| Grant date | May 1, 2018 |
| Priority date | — |
| Expiry date | Apr 21, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/58
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A process for reducing the particle size of an active pharmaceutical ingredient (API) while maintaining its polymorphic form, comprises the step of processing the active pharmaceutical ingredient by cavitation at elevated pressure. The process preferably comprises the step of isolating the processed active ingredient in the form of powder, wherein the isolation step comprises filtration or spray drying. Particles produced by the process of the invention typically have a span value of less than 2.5.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.