4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide monohydrate

US9957232B2 · kind B2 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Alfons Grunenberg · Wuppertal, DE
• Juergen Stiehl · Winsen (Aller), DE
• Katharina Tenbieg · Dortmund, DE
• Birgit Keil · Düsseldorf, DE

Key dates

• Filing date: Sep 29, 2007
• Grant date: May 1, 2018
• Expiry date: Jul 9, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D213/81
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide monohydrate, to processes for its preparation, to pharmaceutical compositions comprising it and to its use in the control of disorders.