Conjugates of RGD peptides and porphyrin or (bacterio)chlorophyll photosynthesizers and their uses
US9957293B2 · kind B2 · utility
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Key dates
| Filing date | Apr 16, 2012 |
| Grant date | May 1, 2018 |
| Priority date | — |
| Expiry date | Apr 16, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/96411
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Conjugates of porphyrin, chlorophyll and bacteriochlorophyll photosensitizers with RGD-containing peptides or RGD peptidomimetics are provided that are useful for photodynamic therapy (PDT), particularly vascular-targeted PDT (VTP), of tumors and nonneoplastic vascular diseases such as age-related macular degeneration, and for diagnosis of tumors by different techniques.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.